During relapses, symptoms of abdominal pain, diarrhea, and rectal bleeding worsen.
Mouth sores Reduced appetite and weight loss Pain or drainage near or around the anus due to inflammation from a tunnel into the skin fistula Other signs and symptoms People with severe Crohn's disease also may experience: Inflammation of skin, eyes and joints Inflammation of the liver or bile ducts Delayed growth or sexual development, in children When to see a doctor See your doctor if you have persistent changes in your bowel habits or if you have any of the signs and symptoms of Crohn's disease, such as: Abdominal pain Ongoing bouts of diarrhea that don't respond to over-the-counter OTC medications Unexplained fever lasting more than a day or two Unexplained weight loss Request an Appointment at Mayo Clinic Causes The exact cause of Crohn's disease remains unknown.
Previously, diet and stress were suspected, but now doctors know that these factors may aggravate but don't cause Crohn's disease. A number of factors, such as heredity and a malfunctioning immune system, likely play a role in its development. It's possible that a virus or bacterium may trigger Crohn's disease.
Crohns disease causes symptoms and treatments your immune system tries to fight off the invading microorganism, an abnormal immune response causes the immune system to attack the cells in the digestive tract, too.
Crohn's is more common in people who have family members with the disease, so genes may play a role in making people more susceptible. However, most people with Crohn's disease don't have a family history of the disease.
Risk factors Risk factors for Crohn's disease may include: Crohn's disease can occur at any age, but you're likely to develop the condition when you're young. Most people who develop Crohn's disease are diagnosed before they're around 30 years old.
Although Crohn's disease can affect any ethnic group, whites and people of Eastern European Ashkenazi Jewish descent have the highest risk. However, the incidence of Crohn's disease is increasing among blacks who live in North America and the United Kingdom.
You're at higher risk if you have a close relative, such as a parent, sibling or child, with the disease. As many as 1 in 5 people with Crohn's disease has a family member with the disease. Cigarette smoking is the most important controllable risk factor for developing Crohn's disease. Smoking also leads to more-severe disease and a greater risk of having surgery.
If you smoke, it's important to stop. While they do not cause Crohn's disase, they can lead to inflammation of the bowel that makes Crohn's disease worse. If you live in an urban area or in an industrialized country, you're more likely to develop Crohn's disease. This suggests that environmental factors, including a diet high in fat or refined foods, may play a role in Crohn's disease.
Complications Crohn's disease may lead to one or more of the following complications: Crohn's disease affects the thickness of the intestinal wall.
Over time, parts of the bowel can scar and narrow, which may block the flow of digestive contents. You may require surgery to remove the diseased portion of your bowel. Chronic inflammation can lead to open sores ulcers anywhere in your digestive tract, including your mouth and anus, and in the genital area perineum.
Sometimes ulcers can extend completely through the intestinal wall, creating a fistula — an abnormal connection between different body parts. Fistulas can develop between your intestine and skin, or between your intestine and another organ.
Fistulas near or around the anal area perianal are the most common kind. When fistulas develop in the abdomen, food may bypass areas of the bowel that are necessary for absorption.
Fistulas may occur between loops of bowel, into the bladder or vagina, or out through the skin, causing continuous drainage of bowel contents to your skin. In some cases, a fistula may become infected and form an abscess, which can be life-threatening if not treated.
This is a small tear in the tissue that lines the anus or in the skin around the anus where infections can occur.
It's often associated with painful bowel movements and may lead to a perianal fistula. Diarrhea, abdominal pain and cramping may make it difficult for you to eat or for your intestine to absorb enough nutrients to keep you nourished.
It's also common to develop anemia due to low iron or vitamin B caused by the disease. Having Crohn's disease that affects your colon increases your risk of colon cancer.Causes. The exact cause of Crohn's disease remains unknown.
Previously, diet and stress were suspected, but now doctors know that these factors may aggravate but don't cause Crohn's disease. Colitis refers to inflammation of the inner lining of the colon.
There are numerous causes of colitis including infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis. Symptoms of . In the meantime, understanding current theories about the causes of Crohn's disease can help you work with your doctor to explore how various treatments might work to control this condition.
Crohn's disease is an inflammatory bowel disease that mainly causes symptoms in the digestive tract. However, some people experience symptoms elsewhere, including mouth ulcers. Crohn’s disease can trigger nausea and stomach pain, both of which can cause a loss of appetite.
Plus, people might cut back on the amount of food they eat in the hopes of avoiding symptoms like diarrhea. Anemia. The inflammation from Crohn’s disease can cause anemia. Crohn’s disease is an inflammatory bowel disease (IBD,) which affects the intestines by causing inflammation.
This inflammation can trigger abdominal pain, diarrhea, weight loss and malnutrition.